Table 4.
Comparison of clinical characteristics between non-ICU and ICU admission
| Non-ICU admission | ICU admission | P-value | |
|---|---|---|---|
| Subjects, n | 502 | 55 | |
| Male, n (%) | 376 (74.9) | 37 (67.3) | 0.220 |
| Age, years, mean ± SD | 69.89±11.25 | 73.06±9.34 | ,0.001 |
| BMI, mean ± SD | 22.61±3.49 | 21.76±3.86 | 0.019 |
| Comorbidities, n (%) | |||
| Hypertension | 182 (36.3) | 24 (43.6) | 0.282 |
| DM | 94 (18.7) | 16 (29.1) | 0.067 |
| MI history | 20 (4.0) | 4 (7.3) | 0.254 |
| CHF | 24 (4.8) | 7 (12.7) | 0.015 |
| CVA history | 26 (5.2) | 3 (5.5) | 0.930 |
| Allergy history, n (%) | 20 (4.0) | 0 (0.0) | 0.301 |
| Asthma history, n (%) | 92 (18.3) | 11 (20.0) | 0.762 |
| Smoking history, n (%) | |||
| Never | 111 (22.1) | 12 (21.8) | 0.960 |
| Ex-smoker | 231 (46.0) | 29 (52.7) | 0.344 |
| Current smoker | 141 (28.1) | 12 (21.8) | 0.323 |
| Smoking (PY), mean ± SD | 37.93±28.18 | 38.48±27.91 | 0.907 |
| Neutrophilic exacerbation, n (%) | 333 (66.3) | 47 (85.5) | 0.004 |
| ≥1 hospital or ER admission in the previous year, n (%) | 137 (27.3) | 20 (36.4) | 0.156 |
| GOLD classification, n (%) | |||
| 1 | 42 (8.4) | 3 (5.5) | 0.452 |
| 2 | 188 (37.5) | 15 (27.3) | 0.137 |
| 3 | 220 (43.8) | 31 (56.4) | 0.076 |
| 4 | 52 (10.4) | 6 (10.9) | 0.899 |
Abbreviations: ICU, intensive care unit; SD, standard deviation; BMI, body mass index; DM, diabetes mellitus; MI, myocardial infarction; CHF, congestive heart failure; CVA, cerebrovascular accident; PY, pack-year; ER, emergency room; GOLD, Global Initiative for Chronic Obstructive Lung Disease.