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3D structure of NorA efflux pump.
Notes: (A) Homology model of NorA efflux pump with N- and C-terminal domains connected by one cytoplasmic connecting loop. (B) 12 transmembrane α-helices such as I–VI from N-terminal domain and VII–XII from C-terminal domain, and large substrate binding cavity (gray) is marked with a circle that is composed of Helix-I, Helix-II, Helix-IV, and Helix-V from N terminal and Helix-VII, Helix-VIII, Helix-X, and Helix-XI from C terminal.
