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. 2016 Oct 3;11:5003–5014. doi: 10.2147/IJN.S115473

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© 2016 Liu et al. This work is published and licensed by Dove Medical Press Limited

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Apoptosis of U251 cells induced by AuNPs and AgNPs with or without radiation.

Notes: The apoptosis rates of U251 cells treated with 50.76 μM or 10 μg/mL AuNPs or AgNPs, followed by 6 Gy radiation, or without, were determined by flow cytometry using Annexin V-FITC and PI as probes. Representative images and summary of distributions of cell status without and with radiation are shown in (A), (B) and (C), (D), respectively. *P<0.05, ***P<0.001 compared with the control group. ^#P<0.05, ^##P<0.01, ^###P<0.001 compared with the corresponding AuNPs-treated group.

Abbreviations: AgNPs, silver nanoparticles; AuNPs, gold nanoparticles; mas-AgNPs, same mass concentration of AgNPs; mol-AgNPs, same molar concentration of AgNPs; PI, propidium iodide.