Figure 1.

The influence of ICV injection of O-n-octanoylated ghrelin, des-Gln¹⁴-ghrelin, and urocortin 3 on cumulative food intake in freely fed satiated rats.

Notes: After ICV injection of different peptides, cumulative food intake was measured at 1, 2, 4, 8, 12, and 24 hours. The results are shown in (A–F), respectively. Data are presented as mean ± SEM. ^**P<0.01, ^***P<0.001, compared to the vehicle-injected group; ^##P<0.01, ^###P<0.001, compared to the O-n-octanoylated ghrelin-injected group; ^§P<0.05, ^§§P<0.01, ^§§§P<0.001, compared to the des-Gln¹⁴-ghrelin-injected group; n=12 rats in each group.

Abbreviations: ICV, intracerebroventricular; SEM, standard error of the mean.