Figure 6.
The effect of Cur/SLNs-HU-211 (1.0 μM) on the MEK1/ERK1/2 signaling pathway in the CORT-induced major depression model.
Note: Representative Western blot images for CB1, p-MEK1, and p-ERK1/2 protein from PC12 cells.
Abbreviations: Cur, curcumin; Cur/SLNs, Cur-loaded SLNs; Cur/SLNs-HU-211, curcumin and HU-211 coencapsulated solid lipid nanoparticles; CORT, corticosterone; PBS, phosphate-buffered saline.