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. 2016 Oct 3;11:4975–4990. doi: 10.2147/IJN.S109088

Figure 6.

Figure 6

The effect of Cur/SLNs-HU-211 (1.0 μM) on the MEK1/ERK1/2 signaling pathway in the CORT-induced major depression model.

Note: Representative Western blot images for CB1, p-MEK1, and p-ERK1/2 protein from PC12 cells.

Abbreviations: Cur, curcumin; Cur/SLNs, Cur-loaded SLNs; Cur/SLNs-HU-211, curcumin and HU-211 coencapsulated solid lipid nanoparticles; CORT, corticosterone; PBS, phosphate-buffered saline.