Table 1.
Baseline characteristics of study participants from the Alberta Physical Activity and Breast Cancer Prevention Trial (ALPHA, n = 320) and the Breast Cancer and Exercise Trial in Alberta (BETA, n = 400)
| Baseline characteristics | ALPHA | BETA | ||
|---|---|---|---|---|
| Exercisers (n = 160) | Controls (n = 160) | Moderate exercisers (n = 200) | High exercisers (n = 200) | |
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |
| Age (years) | 61.2 ± 5.4 | 60.6 ± 5.7 | 59.5 ± 5.1 | 59.4 ± 4.8 |
| Body composition measurements | ||||
| BMI (kg/m2) | 29.1 ± 4.5 | 29.2 ± 4.3 | 29.4 ± 4.4 | 29.1 ± 4.4 |
| Intra‐abdominal fat area (cm2)a | 101.4 ± 55.4 | 103.2 ± 56.0 | 133.4 ± 49.3 | 125.6 ± 50.8 |
| Total body fat (kg) | 30.9 ± 8.2 | 31.3 ± 8.6 | 31.0 ± 8.7 | 30.8 ± 8.6 |
| Percent body fat | 42.2 ± 4.9 | 42.4 ± 5.7 | 40.7 ± 5.9 | 40.5 ± 5.8 |
| Alcohol intake (g/d) | 4.4 ± 5.9 | 5.0 ± 7.6 | 5.3 ± 7.1 | 5.5 ± 8.5 |
| Total energy intake (kcal/d) | 1551.2 ± 598.7 | 1527.3 ± 535.0 | 1474.0 ± 541.4 | 1462.1 ± 588.2 |
| Past year total physical activity (MET‐h/week) | ||||
| Total physical activity | 114.2 ± 57.6 | 129.1 ± 77.9 | 96.4 ± 48.2 | 93.7 ± 44.1 |
| Occupational activity | 50.4 ± 49.1 | 52.2 ± 57.9 | 35.0 ± 34.5 | 36.4 ± 34.3 |
| Household activity | 52.9 ± 34.3 | 63.9 ± 53.5 | 50.3 ± 33.9 | 48.1 ± 32.7 |
| Recreation activity | 10.2 ± 11.8 | 12.1 ± 13.6 | 9.9 ± 13.6 | 8.5 ± 9.4 |
| Maximal oxygen consumption (mL/kg/min) | 27.1 ± 6.2 | 26.8 ± 6.0 | 26.8 ± 5.0 | 26.7 ± 5.3 |
| n (%) | n (%) | n (%) | n (%) | |
|---|---|---|---|---|
| Full‐time employment | 82 (55) | 79 (51) | 59 (30) | 71 (36) |
| Education beyond high school | 112 (70) | 102 (64) | 155 (78) | 155 (78) |
| Married/common‐law | 113 (71) | 125 (78) | 139 (70) | 136 (68) |
| White/Caucasian | 144 (91) | 145 (91) | 186 (93) | 172 (86) |
| Ever used hormone therapy | 75 (47) | 71 (44) | 55 (28) | 62 (31) |
| Regular NSAID user | 18 (11) | 24 (15) | 18 (9) | 14 (7) |
| Regular statin user | 25 (16) | 18 (11) | 25 (13) | 21 (11) |
| Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | |
|---|---|---|---|---|
| IL‐4 (pg/mL) | 1.57 (0.82–2.11) | 1.70 (0.95–2.42) | 0.83 (0.41, 2.23) | 0.92 (0.46, 2.03) |
| IL‐10 (pg/mL) | 1.35 (0.81–1.90) | 1.48 (0.81–1.87) | 0.79 (0.49, 1.46) | 0.76 (0.45, 1.42) |
BMI, body mass index; IL‐4, interleukin‐4; IL‐10, interleukin‐10; IQR, interquartile range; NSAID, nonsteroidal anti‐inflammatory drug; SD, standard deviation.
a
Different algorithms were used to calculate intra‐abdominal fat area from computerized tomography (CT) scans between ALPHA and BETA.