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. 2016 Aug 12;5(9):2378–2384. doi: 10.1002/cam4.835

Table 1.

Baseline clinical and biological characteristics of the patients studied and summary of the hybrid imaging patterns observed with the two radiopharmaceuticals used

Axial skeleton Spleen Liver Distal skeleton EMH SPECT/CT Disease status and molecular profile
99mTc 111In 99mTc 111In 99mTc 111In 99mTc 111In 99mTc 111In
P1 Fixation Lower fixation Hyperfixation Hyperfixation Hyperfixation Fixation Fixation Higher fixation Neg Neg PMF‐F V617F‐JAK2pos
P2 Fixation Fixation Fixation Hyperfixation Fixation Fixation Fixation Higher fixation Neg Neg PMF‐F JAK2pos (exon12) CALRneg MPLneg
P3 Lower fixation Lower fixation Fixation Hyperfixation Fixation Fixation Fixation Higher fixation Neg Neg PMF‐F JAK2pos (exon12) CALRneg MPLneg
P4 Lower fixation Fixation Fixation Hyperfixation Fixation Fixation Fixation Higher fixation Neg Neg PMF‐F V671F‐ JAK2pos
P5 Lower fixation Fixation Fixation Fixation Fixation Fixation No fixation No fixation Neg Neg Post‐TE‐MF V617F‐JAK2pos
P6 Very low fixation Fixation Fixation Hyperfixation Fixation Fixation Low fixation Higher fixation Neg Neg PMF‐F V617F‐JAK2pos

SPECT/CT, single‐photon emission tomography/computed tomography; EMH, extramedullary hematopoiesis; PMF, primary myelofibrosis.