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. 2016 Oct 7;11(10):e0164137. doi: 10.1371/journal.pone.0164137

Fig 10. Transfection of hFOB 1.19 with iNOS siRNA prevents AgNPs-induced cell death.

Fig 10

The hFOB 1.19 cells were transfected with either 50 nM iNOS or control siRNA for 24 h, then cells were exposed for 48 h to 60 μg/mL AgNPs (the highest working concentration). (A) A representative immunoblot demonstrates efficient of transfection of iNOS siRNA. iNOS siRNA prevents AgNPs-induced increase of (B) NO, (C) NT, (D) apoptosis level and attenuated AgNPs-induced (E) cell death. Data are expressed as means ± SD of 3 independent experiments. **p<0.01; ***p<0.001 exposed cells v/s control or as indicated.