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. Author manuscript; available in PMC: 2016 Oct 7.
Published in final edited form as: J Med Chem. 2015 Oct 20;58(21):8647–8657. doi: 10.1021/acs.jmedchem.5b01245

Figure 1.

Figure 1

Mu opioid agonist 1 and chemokine CCR5 antagonist 2 pharmacophores have been incorporated into the bivalent ligand series (3a-3f) and monovalent control ligands 4, and 5.