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. Author manuscript; available in PMC: 2016 Oct 7.
Published in final edited form as: J Med Chem. 2015 Oct 20;58(21):8647–8657. doi: 10.1021/acs.jmedchem.5b01245

Figure 3.

Figure 3

ED50’s of MCC22 on control or LPS-pretreated mice that were injected (45 mg/kg i.p.) with minocycline prior to testing. LPS/MCC22: 0.015 (0.01 – 0.03); naïve/MCC22: 45.75 (23.05 – 90.81); LPS/minocycline/MCC22: 1016 (54-1558)