Table 3. Levels of hemoglobin (Hb), haptoglobin (Hp) and hemopexin (Hx) associated with HDL in 32 sickle cell disease (SCD) patients and 28 healthy normal donors (Control).

A
ELISA (Relative concentration)	Control(Mean ± SD)	SCD(Mean ± SD)	p*
Hemoglobin	1.00±0.43	3.74±0.31	< 0.001
Haptoglobin	1.00±0.45	1.87±0.68	< 0.001
Hemopexin	1.00±0.34	1.54±0.52	< 0.001
ApoA-1	1.00±0.49	0.72±0.26	< 0.05
B
HDL-captured ELISA	Control(Mean ± SD)	SCD(Mean ± SD)	p*
(Relative concentration)
Hemoglobin	1.00±0.35	2.58±1.24	< 0.0001
Haptoglobin	1.00±0.32	2.14±0.79	< 0.0001
Hemopexin	1.00±0.41	1.41±0.51	< 0.05
ApoA-1	1.00±0.32	0.78±0.42	<0.05
C
ApoA-1-captured ELISA	Control(Mean ± SD)	SCD(Mean ± SD)	p*
(Relative concentration)
Hemoglobin	1.00±0.43	3.02±1.68	< 0.0001
Haptoglobin	1.00±0.38	2.31±0.97	< 0.0001
Hemopexin	1.00±0.21	1.53±0.38	< 0.01
ApoA-1	1.00±0.27	0.97±0.30	NS

ELISA, enzyme-linked immunosorbent assay; SD, standard deviation.

*analyzed by a t-test.