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. 2016 Oct 7;12(10):e1005051. doi: 10.1371/journal.pcbi.1005051

Fig 1. Dimeric interactions of SARAH domains.

Fig 1

(A) Schematic representation of the principal monomeric and dimeric systems modeled in this study. Arrows represent the steps followed to construct our molecular models. (B) MST2-RASSF5 complex from crystal structure (PDB ID: 4LGD) showing the direct interaction between RASSF5 (red) and MST2 (blue) SARAH domains. The MST2 kinase domain (blue) is also resolved in the 4LGD crystal structure (the linker segment between the catalytic and SARAH domains is not resolved).