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. 2016 Oct 7;11(10):e0164068. doi: 10.1371/journal.pone.0164068

Table 1. Patient and disease characteristics and number of recurrences during 10 years' follow-up of 1615 patients with laryngeal squamous cell carcinoma treated during 1983–2010.

Recurrence n = 368 Non-recurrence n = 1247
n % n %
Sex
Male 322 88 1081 87
Female 46 12 166 13
Smoking
Ever 326 89 1108 89
Never 30 8 67 5
Unknown 12 3 72 6
Alcohol
Ever 61 17 162 10
Never 213 58 715 60
Unknown 94 25 370 30
Age (years)
0–59 130 35 328 26
60–69 131 36 411 33
≥70 107 29 508 41
Subsite
Glottic 243 66 884 71
Supraglottic 113 31 324 26
Subglottic 12 3 39 3
T-status
T1 90 24 577 46
T2 120 33 267 21
T3 85 23 146 12
T4 73 20 257 21
N-status
N0 300 82 1043 84
N1 23 6 76 6
N2+ 45 12 128 10
M-status
M0 368 100 1233 99
M1 0 0 14 1
Stage
Early stage 194 53 789 63
Advanced stage 174 47 458 37
Stage I-IV
I 87 24 563 45
II 107 29 223 18
III 76 21 146 12
IV 98 26 315 25
Treatment modality
Radiotherapy 271 74 737 59
Transoral lasermicrosurgery 38 10 294 24
Total laryngectomy 41 11 138 11
Chemo-radiotherapy 18 5 37 3
Palliative/ no treatment 0 0 41 3
Period of treatment
1983–1989 113 31 289 23
1990–1996 89 24 288 23
1997–2003 93 25 309 25
2004–2010 73 20 361 29
Length of follow-up
<1 year 183 50 222 18
1–2 years 143 39 239 19
3–5 years 34 9 237 19
6–10 years 8 2 549 44