Table 1. Patient and disease characteristics and number of recurrences during 10 years' follow-up of 1615 patients with laryngeal squamous cell carcinoma treated during 1983–2010.
Recurrence n = 368 | Non-recurrence n = 1247 | |||
---|---|---|---|---|
n | % | n | % | |
Sex | ||||
Male | 322 | 88 | 1081 | 87 |
Female | 46 | 12 | 166 | 13 |
Smoking | ||||
Ever | 326 | 89 | 1108 | 89 |
Never | 30 | 8 | 67 | 5 |
Unknown | 12 | 3 | 72 | 6 |
Alcohol | ||||
Ever | 61 | 17 | 162 | 10 |
Never | 213 | 58 | 715 | 60 |
Unknown | 94 | 25 | 370 | 30 |
Age (years) | ||||
0–59 | 130 | 35 | 328 | 26 |
60–69 | 131 | 36 | 411 | 33 |
≥70 | 107 | 29 | 508 | 41 |
Subsite | ||||
Glottic | 243 | 66 | 884 | 71 |
Supraglottic | 113 | 31 | 324 | 26 |
Subglottic | 12 | 3 | 39 | 3 |
T-status | ||||
T1 | 90 | 24 | 577 | 46 |
T2 | 120 | 33 | 267 | 21 |
T3 | 85 | 23 | 146 | 12 |
T4 | 73 | 20 | 257 | 21 |
N-status | ||||
N0 | 300 | 82 | 1043 | 84 |
N1 | 23 | 6 | 76 | 6 |
N2+ | 45 | 12 | 128 | 10 |
M-status | ||||
M0 | 368 | 100 | 1233 | 99 |
M1 | 0 | 0 | 14 | 1 |
Stage | ||||
Early stage | 194 | 53 | 789 | 63 |
Advanced stage | 174 | 47 | 458 | 37 |
Stage I-IV | ||||
I | 87 | 24 | 563 | 45 |
II | 107 | 29 | 223 | 18 |
III | 76 | 21 | 146 | 12 |
IV | 98 | 26 | 315 | 25 |
Treatment modality | ||||
Radiotherapy | 271 | 74 | 737 | 59 |
Transoral lasermicrosurgery | 38 | 10 | 294 | 24 |
Total laryngectomy | 41 | 11 | 138 | 11 |
Chemo-radiotherapy | 18 | 5 | 37 | 3 |
Palliative/ no treatment | 0 | 0 | 41 | 3 |
Period of treatment | ||||
1983–1989 | 113 | 31 | 289 | 23 |
1990–1996 | 89 | 24 | 288 | 23 |
1997–2003 | 93 | 25 | 309 | 25 |
2004–2010 | 73 | 20 | 361 | 29 |
Length of follow-up | ||||
<1 year | 183 | 50 | 222 | 18 |
1–2 years | 143 | 39 | 239 | 19 |
3–5 years | 34 | 9 | 237 | 19 |
6–10 years | 8 | 2 | 549 | 44 |