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. 2016 Oct 7;11(10):e0164215. doi: 10.1371/journal.pone.0164215

Fig 4. Sodium bicarbonate slightly enhances Aristolochia manshuriensis Kom-mediated renal nephrotoxicity.

Fig 4

Alterations in (A) female and (B) male BUN and, (C) female and (D) male CRE levels in the four rat cohorts. (E) H&E staining of female rat kidney tissue in the four rat cohorts. (F) Histological damage score and (G) inflammation degree of the female kidney in four cohorts. (H) H&E staining of male rat kidney tissue in the four cohorts. (I) Histological damage score and (J) inflammation degree of the male kidney in four cohorts. CTL, control; AMK, Aristolochia manshuriensis Kom; SB, sodium bicarbonate; S+A, sodium bicarbonate and AMK. Data are expressed as mean ± SEM. *P<0.05 vs. CTL cohort; ***P<0.001 vs. CTL cohort; # P<0.05 vs. AMK cohort; n = 5.