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qPCR analysis of hepatic (A) Cyp 1a1, (B) Cyp 1a2, (C) Cyp 3a1, (D) Cyp 2e1, (E) Cpr and renal (F) Cyp 1a1 mRNA levels in the four rat cohorts. CTL, control; AMK, Aristolochia manshuriensis Kom; OM, omeprazole; O+A, omeprazole and AMK. Data are expressed as mean ± SEM. *P<0.05 vs. CTL cohort; **P<0.01 vs. CTL cohort; ***P<0.001 vs. CTL cohort; # P<0.05 vs. AMK cohort; ## P<0.01 vs. AMK cohort. n = 6.
