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Histopathologic features of arteriolosclerosis in the forebrain white matter of HIV-infected adults. On hematoxylin and eosin staining, arteriolosclerosis is defined as concentric intramural hyalinization of small arteries or arterioles and graded as absent (normal, with intactness of vascular smooth muscle cells) (a, arrow), mild (partial thickness involvement) (b, arrows), and severe (full-thickness involvement) (c, arrow); scale bar: 100 µm
