Table 1.
Stem/progenitor cell | Surrounding environment | Key regulators | Metabolic pathway |
---|---|---|---|
Mesenchymal stem cell | Hypoxia | Hif-1α | Glycolysis |
Chondroblast | Hypoxia | Glycolysis | |
Osteoblast | Not available | OXPHOS | |
Neural stem cell | Hypoxia | Foxo3 | Low glycolysis |
Neural progenitor | Normoxia | Acetyl-CoA transferase | Fatty acid synthesis |
Hematopoietic stem cell | Hypoxia | Hif-1α | Glycolysis |
mTOR | Mitochondrial metabolism, ROS | ||
Pml-Pparδ | Fatty acid oxidation | ||
Foxo | Glycolysis, ROS | ||
Lkb1 | Mitochondrial biogenesis | ||
Embryonic stem cell | Not applicable | Pentose phosphate pathway | Glycolysis, low OXPHOS |