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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Biomaterials. 2016 Sep 19;109:69–77. doi: 10.1016/j.biomaterials.2016.09.013

Figure 4.

Figure 4

Multimodal image-guided surgical resection of HCC using IA targeted anti-CD44-Nd-CSUCNP imaging reporters, (a) MR T2 weighted images of rats after IA delivery confirming HCC detection of anti-CD44-Nd-CSUCNP imaging reporters, (b) digital imaging of HCC lesion, (c) detection of HCC with UCL imaging of IA targeted anti-CD44-Nd-CSUCNPs and NIR light (808 nm), (d) an image of liver after image-guided hepatic electro-cauterization resection, (inset) UCL imaging of resected HCC tissue with NIR light (808 nm), (e) representative H&E histologic images of resected tissues (center and peripheral tissues) with multimodal image guidance using anti-CD44-Nd-CSUCNP imaging reporters and remnant liver tissues.