Fig. 5.

Effect of recombination deficiencies on spontaneous rates of tandem repeat recombination events. The recombination reporter plasmid containing the tandem repeat cassette called KanKanMX4 (Ede et al. 2011) contains an internal 266 bp duplication which leads to inactivation of the kanamycin resistance gene. Loss of the repeated sequence is scored by restoration of kanamycin resistance. The spontaneous reversion rates were measured as described (see Supplementary Methods). Spontaneous rates are given relative to the respective spontaneous rate in wild type cells, which was set to 1