Table 3.
Allele and genotypes frequencies distribution of ELMO1 variants in DN and DM subjects
| SNP ID | Allele/Genotype | DN (n = 100) N (%) |
DM (n = 100) N (%) |
p value | OR (95 % CI) |
|---|---|---|---|---|---|
| rs1345365 | A | 143 (71.5) | 153 (76.5) | 0.2 | 0.7 (0.4–1.2) |
| G | 57 (28.5) | 47 (23.5) | 0.2 | 1.2 (0.8–2) | |
| AA | 51 (51) | 58 (58) | 0.3 | 0.7 (0.4–1.3) | |
| AG | 41 (.41) | 37 (37) | 0.5 | 1.1 (0.6–2) | |
| GG | 8 (8) | 5 (5) | 0.3 | 1.6 (0.5–5.2) | |
| HWE | 0.9 | 0.7 | |||
| rs741301 | A | 106 (53) | 133 (66.5) | 0.005 | 0.5 (0.3–0.8) |
| G | 94 (47) | 67 (33.5) | 0.005 | 1.7 (1.17–2.63) | |
| AA | 32 (32) | 45 (45) | 0.05 | 0.5 (0.3–1) | |
| AG | 42 (42) | 43 (43) | 0.8 | 0.9 (0.5–1.6) | |
| GG | 26 (26) | 12 (12) | 0.01 | 2.5 (1.2–5.4) | |
| HWE | 0.1 | 0.7 |
HWE Hardy-Weinberg equilibrium, DN Type 2 diabetes with Nephropathy, DM Type 2 diabetes without Nephropathy