Table 4.
Summary of diagnostic sensitivity of 10-biomarker panel and voided urinary cytology in patients with bladder cancer
| No of bladder cancer cases predicted by biomarker assay | AUC | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|
| Overall | 179 of 211 | 0.895 | 84.8 | 80.6 |
| Low-grade tumors | 63 of 87 | 0.849 | 72.4 | 82.1 |
| High-grade tumors | 112 of 124 | 0.932 | 90.3 | 85.1 |
| NMIBC | 139 of 170 | 0.878 | 81.8 | 80.6 |
| MIBC | 35 of 41 | 0.961 | 85.4 | 95.5 |
NMIBC non-muscle invasive bladder cancer, MIBC muscle invasive bladder cancer, AUC Area under ROC curve