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. Author manuscript; available in PMC: 2016 Oct 8.
Published in final edited form as: Mol Pharm. 2015 May 12;12(6):2093–2100. doi: 10.1021/mp500875f

Figure 2.

Figure 2

Effects of CPA and M-CPA on cell viability and SHH pathway in Miapaca-2, Panc-1 and HPSC cells. (A) CPA release profiles at 37 °C in pH7.4 and pH 5.2 buffers. (B-D) Cell viability after treatment with free CPA and M-CPA. Data points are presented as mean ± standard error of mean (N = 6) (E) Expression of SHH pathway proteins in Miapaca-2, Panc-1 and HPSC cells after treatment with CPA and M-CPA (both at 10 M CPA equivalent concentration). 30 μg protein was loaded into each lane for immunoblotting.