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. Author manuscript; available in PMC: 2017 Oct 8.
Published in final edited form as: Bioorg Med Chem. 2016 Apr 8;24(11):2530–2543. doi: 10.1016/j.bmc.2016.04.019

Scheme 5.

Scheme 5

Reagents and conditions: i) N-(4-bromophenyl)-2-chloroacetamide, K2CO3, anhydrous CH3CN, reflux, 6 h; ii) 3-methoxybenzenboronic acid, (CH3COO)2Cu, Et3N, anhydrous CH2Cl2, rt, 16 h.