Table 3.
Visceral organ weights of rats gavaged daily with water, low-dose or high-dose rhubarb extract (1 mL) during an 8-d trial period and administered with an intraperitoneal injection of saline or 5-fluorouracil on day 5
| Water + saline | Water + 5-FU | LDR + 5-FU | HDR + 5-FU | |
| Thymus | 14.6 ± 1.3 | 6.6 ± 0.5e | 9.4 ± 0.6 | 9.5 ± 0.9 |
| Heart | 37.5 ± 0.8 | 39.0 ± 1.0 | 39.4 ± 0.8 | 39.1 ± 0.7 |
| Lung | 60.0 ± 2.2 | 63.0 ± 2.5 | 67.3 ± 4.7 | 71.9 ± 3.0 |
| Liver | 362.9 ± 6.5 | 362.7 ± 11.0 | 358.8 ± 7.2 | 339.7 ± 7.2 |
| Spleen | 20.3 ± 0.5 | 15.6 ± 0.3e | 15.2 ± 0.4 | 14.6 ± 0.5 |
| Kidneys | 75.6 ± 5.3 | 86.5 ± 1.7 | 88.7 ± 1.1 | 89.4 ± 2.7 |
| Caecum | 39.7 ± 1.1 | 43.7 ± 2.4 | 49.2 ± 2.5 | 47.0 ± 2.1 |
| Stomach | 57.3 ± 2.6 | 55.3 ± 1.1 | 58.8 ± 0.9 | 61.9 ± 1.2 |
e
P < 0.001 vs water + saline. All values are expressed as mean [% relative to bodyweight (× 10-2)] ± SEM. LDR: Low-dose RE; HDR: High-dose RE; RE: Rhubarb extract.