Table 1.
Characteristics | Total | IL28B CC | IL28B non-CC | P value |
n = 108 | n = 19 | n = 89 | ||
Age (yr), median | 53.5 (22.0-68.3) | 48.2 (22.1-66.4) | 53.8 (22.1-68.3) | 0.137 |
Female | 64 (59.3) | 8 (42.1) | 56 (62.9) | 0.094 |
Residence urban | 78 (72.2) | 17 (87.5) | 61 (68.5) | 0.090 |
Baseline ALT (mg/dL), median | 76.5 (16-890) | 103 (16-890) | 74 (17-256) | 0.031 |
Baseline HCV-RNA (log10IU/mL), median | 6.1 (4.15-7.3) | 6.2 (4.15-7.2) | 6.1 (4.15-7.3) | 0.333 |
Mild/moderate fibrosis | 38 (58.5) | 9 (69.23) | 29 (55.8) | 0.470 |
Absence of core mutations - DW | 13 (12.0) | 6 (31.6) | 7 (7.9) | 0.011 |
RVR (%) | 14 (13.0) | 7 (36.8) | 7 (7.9) | 0.003 |
EVR (%) | 43 (39.8) | 16 (84.2) | 27 (30.3) | < 0.001 |
SVR (%) | 42 (38.9) | 17 (89.5) | 25 (28.1) | < 0.001 |
HCV: Hepatitis C virus; DW: Double wild-type; SVR: Sustained virological response; EVR: Early virological response; RVR: Rapid virologic response.