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. 2016 Oct 7;22(37):8414–8434. doi: 10.3748/wjg.v22.i37.8414

Table 11.

Study definitions of good response according to magnetic resonance imaging tumour regression grade scales

Ref. Year TRG scale used (histological stage based upon) Scales accurate? Good response definition Total (n) Good responders (n) Average F/up in months LR (%) 5 yr DR (%) 5 yr DFS (%) OS (%)
Shihab et al[52] 2011 MRI TRG (based on Mandard) Yes TRG 1,2,3 37 20 1 3
Patel et al[6] 2012 MRI TRG (based on Dworak) Yes TRG 1,2,3 69 47
Patel et al[5] and Patel et al[7] 2011 and 2012 MRI TRG (based on Dworak) Yes TRG 1,2,3 66 32 60 14 Yr. 5: 64 Yr. 5: 72
Yu[53] 2014 (unpublished data from our centre) MRI TRG (based on Mandard and Dworak) Yes TRG 1,2 152 61 DFS, Yr. 5: 83% DFS, Yr. 5: 90%

LR: Local recurrence; DR: Distant recurrence; DFS: Disease- free survival; OS: Overall survival; TRG: Tumour regression grade.