Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 5;72(11):1353–1361. doi: 10.1007/s00228-016-2102-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 1 — Fitting of the in vitro dissolution behavior of drugs evaluated in drug interaction studies to the Noyes-Whitney formula. a Amlodipine. b Aspirin, dihydroxyaluminum aminoacetate, and magnesium carbonate (Bufferin combination tablet). c Losartan. d Metoprolol ER. e Nifedipine. f Triazolam. Plot: measured value, line: estimated value, R _d.: dissolution rate. The higher k _d value was selected from the results of the dissolution test using the first fluid (pH 1.2) and the second fluid (pH 6.8) for the dissolution test (the 16th edition of the Japanese Pharmacopoeia)