Table 6.
Mean and change from baseline in fasting plasma glucose and plasma glucose 2 hours after breakfast (ITT population).
| 5-ALA-SFC | Placebo | |||||
|---|---|---|---|---|---|---|
| n | Mean | Change from baselinea
Mean (SE) |
n | Mean | Change from baselinea
Mean (SE) |
|
| Fasting plasma glucose (mg/dL) | ||||||
| Week 2 | 33 | 145.1 | 2.3 (3.4) | 14 | 138.4 | −7.3 (5.2) |
| Week 4 | 30 | 142.1 | −0.2 (4.9) | 14 | 145.6 | −0.8 (7.2) |
| Week 6 | 27 | 138.0 | −4.8 (3.2) | 13 | 132.4 | −9.2 (4.7) |
| Week 8 | 22 | 135.8 | −4.5 (4.0) | 12 | 142.7 | −1.0 (5.5) |
| Week 10 | 23 | 140.3 | −0.9 (5.6) | 12 | 143.1 | −0.9 (7.8) |
| Week 12 | 22 | 139.3 | −3.0 (4.4) | 12 | 139.5 | −4.2 (5.9) |
|
| ||||||
| Plasma glucose 2 hours after meal (mg/dL) | ||||||
| Week 2∗ | 33 | 189.6 | −0.2 (5.1) | 14 | 166.3 | −26.5 (7.8) |
| Week 4 | 30 | 175.7 | −12.9 (6.1) | 12 | 173.9 | −18.8 (9.9) |
| Week 6 | 27 | 173.4 | −14.5 (5.4) | 13 | 158.5 | −27.4 (7.8) |
| Week 8 | 20 | 176.2 | −5.6 (5.6) | 11 | 155.0 | −30.5 (11.2) |
| Week 10 | 20 | 175.1 | −10.3 (10.5) | 12 | 181.2 | −7.6 (13.5) |
| Week 12 | 21 | 175.0 | −8.5 (9.8) | 10 | 154.3 | −33.0 (14.2) |
∗ p < 0.05 between groups.
aCompared to baseline mean for only the subjects with a result for the visit.