Table 3. Association Between MAGE-1 Nuclear and Cytoplasmic Expression and Different Clinicopathological Parametersa.
Clinicopathological Parameter | Cytoplasmic Expression | Nuclear Expression | ||||||
---|---|---|---|---|---|---|---|---|
Negative | Positive | P Value | Negative | Positive | P Value | |||
ER status | - | (n = 23) | 15 (65.2) | 8 (34.8) | 0.501 | 16 (69.6) | 7 (30.4) | 0.298 |
+ | (n = 34) | 25 (73.5) | 9 (26.5) | 19 (55.9) | 15 (44.4) | |||
PR status | - | (n = 23) | 15 (65.2) | 8 (34.8) | 0.912 | 16 (69.6) | 7 (30.4) | 0.337 |
+ | (n = 30) | 20 (66.7) | 10 (33.3) | 17 (56.7) | 13 (43.3) | |||
HER2/neu | Pos | (n = 32) | 25 (78.1) | 7 (21.9) | 0.087 | 19 (59.4) | 13 (40.6) | 0.66 |
Neg | (n = 23) | 13 (56.5) | 10 (43.5) | 15 (65.2) | 8 (34.8) | |||
Tumor stage | T1 | (n = 15) | 10 (66.7) | 5 (33.3) | 0.942 | 10 (66.7) | 5 (33.3) | 0.751 |
T2 | (n = 53) | 37 (69.8) | 16 (30.2) | 37 (69.8) | 16 (30.2) | |||
T3 | (n = 18) | 13 (72.2) | 5 (27.8) | 14 (77.8) | 4 (22.2) | |||
Lymph node status | N0 | (n = 9) | 6 (66.7) | 3 (33.3) | 0.003 | 3 (33.3) | 6 (66.7) | 0.042 |
N1 | (n = 25) | 22 (78.6) | 6 (21.4) | 21 (75) | 7 (25) | |||
N2 | (n = 19) | 15 (78.9) | 54 (21.1) | 16 (84.2) | 3 (15.8) | |||
N3 | (n = 8) | 1 (12.5) | 7 (87.5) | 6 (75) | 2 (25) | |||
Tumor grade | I | (n = 9) | 8 (88.9) | 1 (11.1) | 0.119 | 6 (66.7) | 3 (33.3) | 0.718 |
II | (n = 44) | 32 (72.7) | 12 (27.3) | 33 (75) | 11 (25) | |||
III | (n = 40) | 23 (57.5) | 17 (42.5) | 27 (67.5) | 13 (32.5) | |||
Patient age, y | ≤ 46 | (n = 52) | 36 (69.2) | 16 (30.8) | 0.312 | 43 (82.7) | 9 (17.3) | 0.418 |
> 46 | (n = 46) | 36 (78.3) | 10 (21.7) | 35 (76.1) | 11 (23.9) | |||
Tumor Size, cm | ≤ 4 | (n = 51) | 35 (68.6) | 16 (31.4) | 0.137 | 38 (74.5) | 13 (25.5) | 0.018 |
> 4 | (n = 35) | 29 (82.9) | 6 (17.1) | 33 (94.2) | 2 (5.7) |
aValues are expressed as No. (%).