Fig. 4.

Placental nutrient transfer in response to p110α deficiency. Materno-fetal transfer of MeG and MeAIB on D16 (A and C) and D19 (B and D) of pregnancy expressed relative to the exchange surface area (A and B) and/or per gram of fetus (C and D). Mean ± SEM for 8 and 10 litters on D16 (n = 23–36 per fetal genotype, per cross) and 5 and 5 litters on D19 (n = 15–19) for WT and α/+ dams, respectively. *Significantly different to WT littermates (P < 0.05, pairwise comparisons). ^†Significantly different to WT dams (P < 0.05, pairwise comparisons). SA, exchange surface area.