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. 2016 Sep 19;113(40):E5962–E5971. doi: 10.1073/pnas.1604082113

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Fig. 6. — Zn²⁺ inhibits similarly monomeric and dimeric Hv1 channels. (A) Currents in response to a +80-mV voltage pulse in the presence of increasing extracellular Zn²⁺ concentrations on Alexa488-maleimide–labeled Hv1 ΔNΔC channels. (B) Normalized tail currents (I_tail/I_max) versus voltage curves in the presence of increasing extracellular Zn²⁺ concentrations (n = 4). (C) Fluorescence changes (ΔF) in response to a +80-mV voltage pulse in the presence of increasing extracellular Zn²⁺ concentrations. (D) Normalized fluorescence changes (ΔF_tail/ΔF_max) versus voltage curves in the presence of increasing extracellular Zn²⁺ concentrations (n = 4). (E and F) Time constants for (E) Zn²⁺ inhibition and (F) recovery from Zn²⁺ inhibition for dimeric S242C and monomeric S242/ΔNΔC channels.