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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Mol Cell Biochem. 2016 Sep 15;422(1-2):197–206. doi: 10.1007/s11010-016-2821-z

Figure 3. CCPA-induced vascular contractions were higher in Tie2-sEH Tr mice.

Figure 3

(A) CCPA-induced concentration response curves showed higher contractions in Tie2-sEH Tr mice. * indicates p < 0.05 compared to sEH WT. (B) The higher contractions observed in Tie2-sEH Tr mice were inhibited by preincubation of MAs with HET0016 (10 μM), PD58059 (1 μM), or GO6976 (1 μM) for 10 minutes. (*p < 0.05 treated Tie2-sEH Tr vs. non-treated Tie2-sEH Tr mice). (C) Effect of HET0016 (10 μM), PD58059 (1 μM), or GO6976 (1 μM) preincubation for 10 minutes in MAs of sEH WT mice.