Figure 6. Reduced pinacidil-induced vascular relaxation in MAs from Tie2-sEH Tr mice.
In the top panel, (A) and (B) representative traces of concentration-dependent muscle tension generated in response to pinacidil in sEH WT and Tie2-sEH Tr mice, respectively. In the bottom panel, (C) summarizes the quantification of vascular relaxation to pinacidil. * indicates p < 0.05 compared to sEH WT.