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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Mol Cell Biochem. 2016 Sep 15;422(1-2):197–206. doi: 10.1007/s11010-016-2821-z

Figure 8. Effect of vascular overexpression of sEH (Tie2-sEH Tr mice) on vascular response in MAs.

Figure 8

The schematic diagram represents the endothelial overexpression of sEH induces A1AR-dependent vascular contraction with the possible involvement of CYP4A, PKCα and ERK1/2 in the downstream. Whereas, endothelial overexpression of sEH reduces the vascular relaxation through KATP channels.