Table 1. Demographic and clinical profiles of the study participants.
Patient ID | Sex/Age, yr | Underlying disease (Pre-existing infection) | Incubation period | CXR infiltrates | Oxygen therapy | Mechanical ventilator | Steroid (Duration) | Antiviral therapy (Duration) | Outcome |
---|---|---|---|---|---|---|---|---|---|
A | M/38 | 2 days | Yes (D6−) | Yes | Yes | Yes (D14–D39) | IFN (D5, D10, D17) + RBV (D5, D10–D20) | Transfer (D61) | |
B | M/65 | 9 days | Yes* (D11−) | Yes | Yes | Yes (D14–D20) | IFN (D11, D18) + RBV (D11) + LPV/r (D11–D20) | Died (D142) | |
C | M/55 | 11 days | Yes* (D5−) | Yes | Yes | No | IFN (D6, D13) + RBV (D6–D14) + LPV/r (D6–D16) | Discharge (D26) | |
D | M/35 | (Bacterial pneumonia) | 6 days | Yes (D5−) | Yes | Yes | Yes (D11–D23) | IFN (D10, D17) + RBV (D10–D23) | Discharge (D33) |
E | F/79 | CHD, Dementia, CKD, Bladder cancer | 12 days | Yes* (D2−) | Yes | Yes† | Yes (D11-D17) | IFN (D12) + RBV (D12–D13) + LPV/r (D12–D13) | Died (D17) |
F | M/55 | DM, CPD, (Lung abscess) | 5 days | Yes* (D1−) | Yes | No | Yes (D14–D16) | No | Discharge (D31) |
G | M/56 | 6 days | Yes* (D4−) | Yes | No | No | IFN (D8, D15) + RBV (D8–D14) + LPV/r (D8-D17) | Discharge (D40) | |
H | M/71 | DM, CVA (Aspiration pneumonia) | 6 days | Yes* (D2−) | Yes | No | No | No | Discharge (D38) |
I | F/77 | DM, Asthma | 7 days | Yes* (D11-) | Yes | No | No | No | Discharge (D18) |
J | M/76 | DM, CHD | 10 days | Yes* (D6−) | No | No | No | No | Discharge (D28) |
K | M/59 | CHD | 2 days | Yes* (D9−) | No | No | No | IFN (D9) + RBV (D9–D13) | Discharge (D19) |
L | F/56 | 4 days | Yes* (D12−) | No | No | No | No | Discharge (D21) | |
M | M/56 | DM, CHD, CLD (Tuberculosis) | 7 days | Yes* (D3−) | No | No | No | No | Discharge (D16) |
N | F/54 | 7 days | Yes* (D3−) | No | No | No | No | Discharge (D21) | |
O | M/46 | 9 days | Yes (D9−) | No | No | No | No | Discharge (D12) | |
P | M/35 | 11 days | No | No | No | No | IFN (D4) + RBV (D4) | Discharge (D14) | |
Q | M/52 | DM (Liver abscess) | 14 days | Yes* (D2−) | No | No | No | IFN (D2, D8) + RBV (D2) + LPV/r (D2–D11) | Discharge (D21) |
CXR = chest X-ray, CHF = chronic heart disease, CKD = chronic kidney disease, DM = diabetes mellitus, CPD = chronic pulmonary disease, CVA = cerebrovascular accident, CLD = chronic liver disease, IFN = pegylated interferon alpha-2a, RBV = ribavirin, LPV/r = ritonavir boosted lopinavir.
*The first chest radiography showed infiltrates; †This patient refused intubation.