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EC50 and Emax values for the inhibition of TNF‐α generation by EP receptor agonists
| Agonist | EC50 (nM) | Emax (%) |
|---|---|---|
| PGE2 | 2.1 ± 0.6 | 77 ± 3 |
| Misoprostol | 54 ± 9.1 | 80 ± 4 |
| L‐902688 | 0.3 ± 0.1 | 63 ± 7 |
| Butaprost | 878 ± 340 | 67 ± 5 |
| ONO‐AE1‐259 | 82 ± 24 | 43 ± 4 |
Experimental details relevant to this Table can be found in the legend of Figure 4. Values are means ± SEM from five (misoprostol, l‐902,688, ONO‐AE1‐259), six (butaprost) and eight (PGE2) experiments.
