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Patient derived xenografts—a novel preclinical mouse model. Genomic sequencing of patient derived xenografts from patients with gastric cancer identifies the molecularly distinct gastric cancer subtypes. In this graph each row represents a patient derived xenograft (PDX). Ten PDXs have been analyzed with 7 tumors clustering with the chromosomal instability (CIN) subtype, 1 with the microsatellite instability (MSI), subtype and 2 genomically stable.
