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| Differentiation | Grade | Proliferative rate |
|---|---|---|
| Well differentiated | G1 (low) | <2 mitoses/10 hpf and Ki-67 index <3% |
| G2 (intermediate) | 2–20 mitoses/10 hpf or Ki-67 index 3–20% | |
| Poorly differentiated | G3 (high) | >20 mitoses/10 hpf or Ki-67 index >20% |
GEP, gastroenteropancreatic; NETs, neuroendocrine tumors; hpf, high-power field.
