Table 2.

Summary of ROCK and MLCK signaling pathways in gastrointestinal intestinal disorders with increased intestinal permeability.

Diseases	Species	Signaling pathway	Reference
IBD	Human	MLCK	Blair et al., 2006 [45]
	Human	ROCK	Segain et al., 2003 [82]
Celiac disease	Human	ROCK	Monsuur et al., [83]
IBS	Human and mice	MLCK or ROCK	Gecse et al., 2008 [84]