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. 2016 Oct 10;6:35063. doi: 10.1038/srep35063

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The distribution of DNA methylation levels throughout the pig genome was analyzed. To compare DNA methylation ra stes among samples, read depth was normalized to the overall average amount of reads in each group, and then a 1 Mb sliding window was used to smooth the distribution. CpG_o/e ratio, SNP density, gene, repeat and CGI were all calculated based on this 1 Mb sliding window.