Figure 1. Schematic representation of CoFe₂O₄ synthesis and Au iterations from 1–5 to enhance the SPR property.

The surface is modified by attaching activated folic acid for specific targeting of cancer cells and also binding with anti-cancer drug doxorubicin for efficient chemotherapy. Finally, the whole complex is employed as MRI contrast agent and microwave based hyperthermal cargo at 2.45 GHz to track and treat cancer cells with high localization.