Table 6.
Effects of miR-21, lenti PTEN and VEGF siRNA on proliferation, apoptosis and angiogenesis of CMEC cells.
| Group | Control | NC | MiR-21 mimics | MiR-21 inhibitors | MiR-21 mimics + lenti PTEN | MiR-21 mimics + VEGF siRNA |
|---|---|---|---|---|---|---|
| Proliferation | 1.00±0.06 | 0.98±0.03 | 1.21±0.08*# | 0.72±0.06*#@ | 1.08±0.07@& | 1.07±0.07@& |
| Apoptosis,% | 9.95±1.50 | 9.85±0.75 | 10.04±1.13 | 32.99±1.51*#@ | 9.87±1.48& | 10.02±1.32& |
| Tube length, mm | 13.17±0.45 | 13.82±0.60 | 22.60±0.90*# | 11.77±0.45*#@ | 17.24±0.53*#@& | 16.33±0.47*#@& |
| Branch point | 35.81±3.26 | 36.44±4.07 | 54.94±5.29*# | 29.71±4.48*#@ | 46.78±3.74*#@& | 43.25±3.64*#@& |
*
P<0.05 versus control group;
#
P<0.05 versus NC group;
@
P<0.05 versus miR-21 mimics group;
&
P<0.05 versus miR-21 inhibitors group.