Table 2.
Characteristics of Crohn’s Disease Patients with and Without Irritable Bowel Syndrome–like Symptoms
| Inactive CD | IBS (+) (n = 29) | IBS (−) (n = 78) | P-value |
|---|---|---|---|
| Age | 39.7 ± 9.1 | 38.3 ± 10.7 | 0.379 |
| Sex (male/female) | 22/7 | 60/18 | 1.000 |
| BMI | 21.5 ± 4.3 | 22.3 ± 12.1 | 0.769 |
| Duration of disease (yr) | 16.0 ± 8.5 | 11.0 ± 6.7 | 0.021 |
| Disease location (proctitis/left/total colitis) | 6/17/6 | 15/50/13 | 0.854 |
| Operation history | 12 (41.4%) Ileal resection: 3 cases Ileocecal resection: 8 cases Colonic resection: 1 case |
32 (41.0%) Ileal resection: 6 cases Ileocecal resection: 22 cases Colonic resection: 4 cases |
0.384 |
| Disease treatment | |||
| 5-ASA/sulfasalazine | 10 | 27 | 1.000 |
| Steroid | 0 | 0 | - |
| AZA/6MP | 5 | 22 | 0.320 |
| Anti-TNF | 20 | 43 | 0.270 |
| Anti-anxiety drug | 4 (13.8%) | 2 (2.5%) | 0.045 |
| Smokers | 5 (17.2%) | 8 (10.3%) | 0.515 |
| CDAI | 115.4 ± 49.6 | 97.2 ± 58.2 | 0.141 |
CD, Crohn’s disease; IBS, irritable bowel syndrome; BMI, body mass index; 5-ASA, 5-aminosalicylate; AZA, azathioprine; 6-MP, 6-mercaptopurine; TNF, tumor necrosis factor; CDAI, CD activity index.
Data are expressed as mean ± SD.