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. 2016 Oct 1;22(4):686–693. doi: 10.5056/jnm15190

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© 2016 The Korean Society of Neurogastroenterology and Motility

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of Dai-kenchu-to (DKT) on colorectal distention (CRD)-induced visceromotor response (VMR). (A) CRD-induced VMR and (B) amplitude over the baseline. Data are expressed as the mean ± SE (n = 6 rats/group). VMR (two-way ANOVA): group effects (F = 41.5, P < 0.001), stimulus effects (F = 18.9, P < 0.001), and group stimulation interactions (F = 7.9, P < 0.001). Amplitude of electromyography: group effect (F = 15.6, P < 0.001), stimulus effect (F = 8.9, P < 0.001), and group × stimulation interaction effects (F = 3.6, P = 0.012). *P < 0.05, **P < 0.01 (vs vehicle). VeCRD, vehicle and colorectal distention; DKTCRD, DKT and CRD.