Figure 5.

Platelet activity prior to and following trauma. Platelet activity was determined by dilution of whole blood and activation with vehicle or adenosine diphosphate (ADP). P-selectin expression and integrin αIIbβ3 activation were determined by the binding of fluorescein isothiocynanate (FITC)-labeled antibody against P-selectin (A) and AF647-labeled fibrinogen (B). Platelet activation tendency was determined by the ratio of the mean fluorescence intensity (MFI) of ADP- and vehicle-stimulated platelets. Data are presented as mean with error bars representing standard deviation (SD).