Fig 6. Bitter taste receptor agonists increase Tc99m albumin nanocolloid bronchial mucociliary clearance in guinea pig.
A) Micro-CT coupled to SPECT representative image of aerosolized Tc99m albumin nanocolloids at time 0 and 360 min in presence or absence of chloroquine, denatonium and saccharin. B) Effects of bitter taste agonists chloroquine, denatonium and saccharin on % Tc99m albumin nanocolloids radiation intensity. Representative images of n = 12 guinea pig per condition are showed. Colorimetric intensity scale adjusted for all images is shown. 100% Tc99m albumin nanocolloids intensity corresponds to the start of experiments (t = 0min) for all experimental conditions). Results are expressed as mean ± SD. One-way repeated measures analysis of variance (ANOVA): P<0.01. Post hoc Bonferroni test: *P<0.05 compared with controls.