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. 2016 Oct 10;11(10):e0164258. doi: 10.1371/journal.pone.0164258

Fig 7. HMGA1 confers breast cancer cells a survival advantage with respect to DNA damaging agents.

Fig 7

A. Colony formation assay performed on MDA-MB-231_shCTRL and MDA–MB–231_shA1_3 cells (A) and MCF7_CTRL and MCF7_HMGA1a cells (B). Cells were treated with doxorubicin (Dox) to induce DNA damage (not treated—NT), then left to grow, fixed, stained with 0.5% crystal violet, and counted. In the upper panel is shown the representative images of the colony assay, in the lower panel is shown the quantification of the colony formation assay as the mean number of colonies/cm2 ± SD (n = 4). P value: ** < 0.01; *** < 0.001.