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Effect of late initiation of sirolimus on renal p-S6 (A), p-4E-BP1 (B) and p-Akt. Representative photomicrographs of immunostaining for p-S6, p-4EBP1 and p-Akt in the kidney at week 20 from Lewis and LPK rats treated from week 10 until week 20. Scale bar = 100μm.
