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. 2016 Oct 10;11(10):e0164312. doi: 10.1371/journal.pone.0164312

Fig 3. The use of systemic immunomodulatory treatment in patients with juvenile idiopathic arthritis associated uveitis.

Fig 3

Treatment at the age of 18, 22 and 30 years with uveitis onset before (<) and after (≥) the year 1990. DMARD = disease modifying anti-rheumatic drugs. A biological was always given combined with a DMARD (in the figure noted as ‘Biologicals’), a DMARD/other drugs were usually given as combination therapy. ‘n = ‘ = total number of patients included in the bar. The exact treatment, with number of patients using this treatment in brackets, was: Treatment 18 years, <1990: Corticosteroids (n = 1). Treatment 18 years, ≥ 1990: Corticosteroids (n = 1), Methotrexate (n = 31), Mycophenolate motefil (n = 2), Azathioprine (n = 2), Cyclosporine (n = 1), Adalimumab (n = 16), Etanercept (n = 1), Infliximab (n = 2). Treatment 22 years, < 1990: Corticosteroids (n = 1), Methotrexate (n = 1).Treatment 22 years, ≥ 1990: Corticosteroids (n = 2), Methotrexate (n = 9), Mycophenolate motefil (n = 3), Azathioprine (n = 1), Hydroxychloroquine (n = 2), Adalimumab (n = 4), Etanercept (n = 2), Tocilizumab (n = 2), Infliximab (n = 1).Treatment 30 years, <1990: Corticosteroids (n = 4), Methotrexate (n = 5), Mycophenolate motefil (n = 1), Hydroxychloroquine (n = 1), Cyclosporine (n = 1), Sulfasalazine (n = 1), Tocilizumab (n = 1), Etanercept (n = 1).