Table 1. Participant demographic and clinical characteristics.
| HC (n = 71) | GHR-SZ (n = 31) | FE-SZ (n = 60) | Statistic value | p value (2 Tailed) | |
|---|---|---|---|---|---|
| Age (years) | 20.63 ± 3.48 (14–25) | 18.39 ± 3.37 (13–24) | 18.32 ± 3.09 (13–25) | F = 9.52 | <0.001 |
| Gender (M / F) | 27 / 44 | 21 / 10 | 29 / 31 | χ2 = 27.66 | <0.05 |
| Medication at the time of scan (Y / N) | N/A | 1* / 30 | 28 / 32 | χ2 = 17.76 | <0.001 |
| Medication-CPZ Equivalent | - | - | 223.86±193.51 | N/A | N/A |
| Duration of illness (months) | N/A | N/A | 8.06 ± 14.02 | N/A | N/A |
| BPRS total score | N/A | 15.52 ± 6.51 | 36.58 ± 12.78 | t = 51.75 | <0.001 |
HC: healthy controls; GHR-SZ: genetic high-risk schizophrenia; FE-SZ: first-episode schizophrenia; BPRS: Brief Psychiatric Rating Scale.
Age is expressed as means ± standard deviations (SD) with range in parentheses. Duration of illness and BPRS score are expressed as means ± SD.